髓系、淋巴、混合系白血病易位基因10抗體（）
英文名稱： Anti-AF10/MLLT10 濃度： 1mg/1ml
抗體來(lái)源：Rabbit
克隆類(lèi)型：polyclonal
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產(chǎn)品類(lèi)型: 一抗
性 狀:Lyophilized or Liquid
保存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 ：A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t（10;11）（p12;q23） with MLL/HRX. The result is a rogue activator protein.
A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t（10;11）（p13;q14） with PICALM.
Function : Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA.
Subunit : Self-associates. Interacts with FSTL3 isoform 2; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with YEATS4. Interacts with SS18. Interacts with DOT1L.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed abundantly in testis.
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR.
DISEASE : Note=A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t（10;11）（p12;q23） with MLL/HRX. The result is a rogue activator protein.
Note=A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t（10;11）（p13;q14） with PICALM.
Similarity : Contains 2 PHD-type zinc fingers.
Database links : UniProtKB/Swiss-Prot: P55197.1
公司對(duì)外提供生物技術(shù)外包服務(wù)：卡邁舒（上海）生物科技專(zhuān)業(yè)經(jīng)營(yíng)一抗二抗,單克隆多克隆抗體,指標(biāo)上千萬(wàn)種,質(zhì)量好,價(jià)格實(shí)惠,售后問(wèn)題負(fù)責(zé)到底,
單克隆抗體定制服務(wù)，多克隆抗體定制，單克隆抗體純化 ，多克隆抗體純化 ，
抗體HRP標(biāo)記 ，抗原HRP標(biāo)記 ，抗體膠體金標(biāo)記，抗體FITC標(biāo)記，小鼠單抗Ig類(lèi)/亞類(lèi)鑒定，獸用細(xì)胞水平檢測(cè)（比如干擾素等），多肽半抗原的偶聯(lián)，
親和層析柱制備 （客戶提供抗原抗體）
環(huán)保在線